由于资金短缺，我们的项目遇到了重大挫折。

Our project experienced a major ___setback due to lack of funding.

这场突如其来的暴风雨让我们的施工计划遇到了重大挫折。

The unexpected storm caused a major ___setback in our construction schedule.

他们在决赛中的失利是一个重大挫折。

Their loss in the final was a major ___setback.