against ·phrase
Definition: If you do something against someone's advice, wishes, etc., you do it although they have said you should not or must not. Level: C2
他不顾医生的劝阻，还是登上了飞机，决心在病魔将他困在床上之前，再见孙子最后一面。
He boarded the flight ___against ___his ___doctor's ___advice, resolved to see his grandson one last time before the illness confined him to bed.
她卖了房子，尽管这违背了他的愿望。
She sold the house even though it was ___against ___his ___wishes.
他继续他的研究，甚至违背了导师们的建议。
He pursued his research even ___against the ___advice of his supervisors.