He looked totally hopped-up after the party, probably from drinking too much.

hopped-up 是形容词，由动词 hop（跳跃）的过去分词 hopped 加上副词 up 组成，字面意思是"跳起来的"，引申为"兴奋的、亢奋的"，常用来形容因药物或酒精作用而产生的异常兴奋状态。