insult

你怎么敢在我朋友面前侮辱我！

How dare you ___insult me in front of my friends!

他的评论是对她智力的直接侮辱。

His comment was a direct ___insult to her intelligence.

嘲笑他人真诚的努力是对他们的侮辱。

To laugh at someone's sincere effort is to ___insult them.