When he heard his favorite show was cancelled, he yelled 'noooooo' in despair.

noooooo 是 no 的夸张拖长写法，通过重复字母"o"和增加长度来表达强烈的拒绝或绝望情绪，类似中文里把"不"拖长说成"不要啊~~~~"的效果。这种非正式拼写常用于网络或口语中表达极度震惊、失望或抗拒。