Their meeting seemed pre-destined from the very beginning.

pre-destined 是由前缀 pre-（表示"预先"）和形容词 destined（注定的）组成的复合词。destined 来自动词 destine（注定），加上 -ed 变成形容词。pre-destined 字面意思是"预先就注定的"，强调某种安排或结果在发生前就已经被决定好了。