他对自己造成的那场误会深感愧疚，这场误会让他失去了最亲密的友情。
He felt personally culpable for the misunderstanding that had cost him his closest friendship.
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解释
culpable 在此指个人因过错而产生的内心自责感。
He felt personally culpable for the misunderstanding that had cost him his closest friendship.
culpable 在此指个人因过错而产生的内心自责感。