sorrow

他对这个消息表示悲痛。

He expressed his ___sorrow at the news.

孤独常常导致深切的悲伤。

Loneliness often leads to deep ___sorrow.

在她的眼中，人们能看到一种深刻而沉默的悲伤。

In her eyes, one could see a profound and silent ___sorrow.