baneful

这种有害的谣言可能会毁掉他的名誉。

Such ___baneful rumors could ruin his reputation.

工厂排放的废水对当地河流有毁灭性的影响。

The factory's waste has a ___baneful effect on the local river.

她最终摆脱了那段有害的关系。

She finally escaped from that ___baneful relationship.